> we contributed upstream to ensure these HTTP clients can route requests directly through the JavaScript `fetch` API in WebAssembly environments

Some context from an urllib3 maintainer:

urllib3 received and merged large contributions adding Pyodide/Emscripten support a few years ago, and later JSPI support, which is what made this work for Requests.

As far as I know, the funding for this work went to the external contributor who implemented it, not to the urllib3 maintainers. We reviewed and merged the changes, and the project is now responsible for maintaining the resulting backend.

This matters because the Emscripten backend is still considered experimental in urllib3, and is explicitly out of scope in our security policy.

CVE-2025-50182 is one example of the problems we've run into. urllib3's redirect controls did not have the expected behavior when requests were routed through `fetch`. There are potentially many more differences like this because browser/`fetch` networking semantics are quite different from urllib3's normal backend.

I'm glad the work was contributed upstream and is useful to Pyodide and Cloudflare. But I think there is a meaningful difference between funding a contribution to an upstream project and funding the upstream maintainers who have to support it afterwards.

Great work from the Cloudflare team!

I was very excited when they first launched Python Workers two years ago. Even though we have competing products at Wasmer, I think Cloudflare work is always exciting and inspiring.

I went back to the feedback I posted in the original launch thread [1]. It's great to see that they have made meaningful progress since then, particularly around package support: PyEmscripten is now standardized through PEP 783.

That said, some of the main architectural concerns I raised at the time are still present:

  * Being tied to use only one version of Python/Pyodide (the one that Workerd embeds)
  * Architecturally tied to the JS/v8 world, which may show some challenges as they aim to reduce cold start times (in my opinion, it will be quite hard for them to achieve <100ms startup time with their current architecture).

The GA announcement doesn't seem to include updated cold-start numbers. Could someone from the Cloudflare team share the current p50/p95 cold-start times for Python Workers, ideally both with and without native user packages? (for example, one with FastAPI and other without any dependencies).

[1] https://news.ycombinator.com/item?id=39907120

[2] https://wasmer.io/posts/wasm-clouds-the-world-after-containe...

They should support Mojo which might be a great fit for edge compute.

All example pages return 404.

Elixir next ;) with clustering across workers (kind of kidding because elixir probably does not make sense for CF workers)

One day it’ll be similarly beautifully trivial to use go too. I hope.

This is the tech at Cloudflare of course, but I swear that my first interpretation of the title was "We have replaced all our python coders with AI and they (the coders) are out and generally available" :-)

Pyodide is such a cool piece of the Python ecosystem. I hope Cloudflare consider throwing some money their direction: https://opencollective.com/pyodide/contribute

How do these perform for cold-starts? I remember one of the disadvantages of using web assembly for Workers was more spin-up time, but maybe they figured out a way around that.