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  • flowerthoughts 1 hours

    If there's no explanation of why the 70+ bucket has so much larger CI band, having that dominate the totals seems like very fair critique. At the very least, they should have presented another totals with the outlier removed to show the impact.

  • bamba890877 3 hours

    [flagged]

  • OutOfHere 2 hours

    Alcohol is a carcinogen, famous for causing various upper gastrointestinal cancers. It also isn't great for brain cells. Why are these reasons not enough to quit it?

    If you want something to drink in the evenings, how about a cup of mild bancha green tea andor rooibos tea andor hibiscus tea? If you do, please get the loose leaf product only, never the bagged product, as the latter infuses microplastics.

    arpinum 38 minutes

    Dose makes the poison. And some substances are beneficial at low doses and harmful at high doses.

    Do you foreswear aspirin?

    jvican 28 minutes

    Agreed - it's all in the dose and the response. Not even mentioning the selection pressure for us to adapt to at least small amounts of alcohol in our diet, which has been present in basic things such as fermented fruits that we had to eat in our ancestral environment.

    readthenotes1 22 minutes

    In small doses, alcohol may have other benefits that outweigh the risk of gastrointestinal cancer.

    Whether it's as strong as the now Resveratrol scam or not is a matter to study honestly, though that quality seems beyond the reach of many humans motivated to prioritize something else.

  • newsomix9xl 3 hours

    I am inclined to take Nassim's position as true, since it agrees with my desired beliefs: that moderate drinking is quite harmless, or if there are harms, they are outweighed by the benefits.

    Modern medicine often gives us access to amazing drugs which have, in small print, a long list of associated, known, proven harms to our organs and health. The logic, as I understand it, is that the benefits of the drugs outweigh the harms.

    The logic is not "that these drugs are harmless and possess only benefits".

    zmgsabst 3 hours

    This is important when discussing (eg) cancer treatments: a treatment may leave you alive for longer but in worse health — and therefore, it’s unclear which is preferable.

    rapidaneurism 2 hours

    Arguably when left alive your health is by definition better than the alternative.

    I suspect you mean the good health for a few months before death compared with a worse health during and after treatment. Still I had to make the quip.

    burnt-resistor 1 hours

    QALY optimization doesn't necessarily optimize for quality of life like it claims on the tin, it optimizes for quantity of life. Would you like 1 year and unknown discomfort or 10 years and a colostomy bag?

    Near end-of-life interventions (in the US) tend to be unnecessary and leave patients worse off, and it's done because hospitals and doctors are greedy.

    https://www.scientificamerican.com/article/surgery-near-end-...

    nkrisc 45 minutes

    Everyone will die. The question is whether, say, two extra months spent in a miserable state is worth it.

    zmgsabst 1 hours

    No — I meant worse health.

    You die in both scenarios, you live slightly longer (eg, 8 months versus 6 months) and during the overlap, you are less healthy than you would have been. Losing 6 months of seeing family, enjoying trips, etc due to side-effects from treatment just to live 2 months extra, but incredibly ill the whole 8 months.

    In my perspective: you experienced less total QALY by taking the treatment and had more time, in worse health. Even counting those 2 months at zero, the non-treatment option experiences more vitality, in total — because 2 sickly months at the end doesn’t offset 6 months of lost vitality immediately before.

  • stevebmark 4 hours

    [flagged]

    scoofy 3 hours

    Nassim Taleb is not publishing AI garbage: https://scholar.google.com/citations?user=64BtMdsAAAAJ&hl=en

    bpodgursky 3 hours

    No, he is famous for publishing his own boutique handcrafted form of garbage.

    benatkin 3 hours

    Flâneur psychosis?

  • nialse 1 hours

    Even the best people seem to go out of their way to rationalise (their own?) alcohol consumption. As a nowadays leading cause of cancer in many regions, and associated with dependency and other secondary negative outcomes, perhaps it is time to stop rationalising it?

    And maybe also let off the rhetoric of "government sponsored" science, which is actually most science in many places. Written for views/clicks obviously. So tiering.

    // Master of Science in Public Health

    free652 18 minutes

    >And maybe also let off the rhetoric of "government sponsored" science, which is actually most science in many places.

    Is it? Government science is usually very closely tied to politics, and that's so far from "science". I didn't see any real science in your post as well btw.

    graemep 15 minutes

    People from puritanical cultures rationalise their opposition to other people consuming alcohol.

    Ad hominem arguments cut both ways.

    laserlight 42 minutes

    The following quote is especially problematic IMHO:

    > For a paper claiming to overturn decades of alcohol drinking recommendations, the statistical foundation is underdocumented and, to be mild, statistically strange.

    Given that "decades of alcohol drinking recommendations" lacked any statistical basis to begin with, the scientific-rigor bar to clear is quite low IMHO.

    nialse 16 minutes

    It's just writing for dramatic effect it seems. The claim that the paper is 'used as “definitive” argument in the medical discussions' seems quite absurd given that the paper itself was published just two months ago.

    jvican 30 minutes

    I think nobody would argue drinking a lot of alcohol, or substantial alcohol, is detrimental for health.

    The question being argued is whether drinking a small amount of alcohol is detrimental to your health. This is a different matter altogether.

    We, humans, have been drinking alcohol for millenia. I'm skeptical to the idea that a small amount, say, a glass of wine for lunch every day or so, can harm us, especially for active individuals. There has been a natural selection process for us to adapt.

    I believe what Taleb is doing here is of great public value, and I commend him for that.

    epolanski 27 minutes

    There is no evidence either small quantities of tobacco or most drugs harm you either.

    People that want to drink will find excuses to do so.

    graemep 12 minutes

    Which "drugs"?

    The problem with highly addictive things is people do not stop at small quantities.

    jvican 23 minutes

    Maybe — I haven't looked at the evidence.

    But, alcohol is something that has been present in our ancestral environment (e.g. fermented fruits). If anyone's telling me, our bodies didn't learn to at least tolerate small amounts of it without any major side effects, I'm going to be asking a lot of follow-up questions.

    I think it's much easier to argue this case than, say, tobacco or "drugs", which are arguably more recent inventions, depending on your exact definition of drug.

    Ekaros 4 minutes

    Same logic applies to heavy metal like lead and others. Also cyanide and arsenic. And so on. We still actively avoid them. Just because we can tolerate them via various process does not mean it wouldn't be better to avoid them altogether and minimise exposure.